Amos explains the ongoing conflict makes 44% of Gaza were uninhabitable or completely penetrated by Palestinians, while residents began to run out of food.
"There are more than 118,000 people sought refuge in UN schools ... people running out of food. Clean water is also a problem," said Amos.
"The situation in Gaza is alarming and also tragic," he added.
More than 710 Palestinians and 30 Israelis were killed in a battle that has been running for 16 days, officials said.
Prime Minister of Israel, Benjamin Netanyahu, said he regretted the loss of life in the Palestinian civilians, but also says it is the responsibility of the Hamas for these casualties.
On the ground, Israeli air and ground operation is continuing and on the other hand Hamas continued to fire rockets into Israel.
Israel began a military operation on July 8 with the aim of halting rocket fire from Gaza.
The supreme leader of Hamas, Khaled Meshaal, stressed not possible truce in Gaza if Israel's economic blockade is not terminated.
Speaking at an international meeting on Gaza in Qatar, Meshaal reiterated Hamas reject ceasefire will continue until fulfillment of the requirements they set.
"We will not accept any initiative that does not lift the blockade on our people and who do not appreciate their suffering," he said.
Statement leader of the radical Palestinian group that comes amid increasingly incessant air strikes and Israeli ground offensive in Gaza.
Israel launched its military offensive July 8, with the announced aim was to stop rocket fire from Gaza.
At least 649 Palestinians and 31 Israelis were killed in 15 days of attacks, Israeli officials demkian information.
On another occasion, the United Nations human rights official, Navi Pillay, condemned the Israeli military action in Gaza.
He also criticized Hamas for 'indiscriminate attack targets' that they have embarked into Israel.
United States Secretary of State John Kerry landed in the capital of Israel despite American airline banned from flying there for 24 hours.
Ban imposed after a rocket fired from the Gaza Strip landed near Ben Gurion Airport in Tel Aviv.
Benjamin Netanyahu before asking John Kerry lifted a ban on American air carriers using the airport in Tel Aviv. Americans step is then made from a number of airlines and countries temporarily stop flight to the city.
Israel says this ban gives Hamas ruling the Gaza Strip propaganda victory that should not be granted.
Kerry visit to Israel on Wednesday (23/07) held when efforts to negotiate a cease-fire between Israel and Gaza continues.
American foreign minister is scheduled to hold talks with UN Secretary General Ban Ki-Moon, Palestinian President Mahmoud Abbas and Israeli Prime Minister Benjamin Netanyahu.
Kerry, Netanyahu and Ban Ki-Moon encourages Hamas accept the outlines of a deal designed by the Egyptians, but Mahmoud Abbas have agreed to the demands put forward by Hamas.
Hamas demanded guarantees that the blockade of the territory by Israel and Egypt revoked. BBC
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